Monday, March 5, 2012

News and Events - 06 Mar 2012




NHS Choices
05.03.2012 19:35:00

“Ice cream 'could be as addictive as cocaine',” reported the Daily Mail. In a bid to scoop its rivals, the newspaper claimed that new research had whipped up “concerns that the dessert could be genuinely addictive”.

It’s not clear who exactly had these chilling “concerns” over the possible addictive qualities of the frozen snack, but the study in question looked at measures of brain activity in 151 teenagers while they drank an ice cream milkshake. During the scans, teenagers who had frequently eaten ice cream over the past two weeks showed less activity in the “reward areas” of the brain that give pleasurable sensations. This reduced reward sensation was reported to be similar to what is seen in drug addiction as users become desensitised to drugs.

It should be noted that the study included only healthy teenagers of normal weight, and its results may not represent overweight or older people. It also only tested one food, so the results may not apply to other foods.

Unsurprisingly, the study did not directly compare brain responses to or cravings for ice cream with those for illegal drugs. Therefore, while some aspects of the brain’s response may be similar, it is not correct to say that this study has found that ice cream is “as addictive” as illegal drugs.

 

Where did the story come from?

The study was carried out by researchers from the Oregon Research Institute in the US. Sources of funding were not clear. The study was published in the peer-reviewed American Journal of Clinical Nutrition.

The newspapers focused on the suggestion that ice cream is “as addictive” as drugs. However, it is  not possible to conclude this from the study.

 

What kind of research was this?

This experimental study looked at whether regularly eating ice cream reduces the brain’s pleasurable “reward” response. When we do things that support our survival, such as eating and drinking, the brain gives us a pleasurable reward sensation, reinforcing this behaviour and encouraging it in future. A similar process is also believed to occur in drug addiction, where a person’s reward response to the drug decreases with repeated exposure, leading to a need to take more of the drug.

The researchers reported that people who are obese experience less of a response to food in the reward centres of the brain, which may contribute to over-eating. Repeatedly eating foods with high levels of calories (called “energy dense” foods has also been shown to lead to brain changes that reduce reward response in rats. The researchers wanted to see if a similar thing happens in humans, by looking at whether regularly eating ice cream reduces the brain’s pleasurable reward response to an ice cream milkshake.

 

What did the research involve?

The researchers recruited 151 adolescent volunteers who were not overweight. They asked them how often they ate ice cream, and carried out brain scans while they drank either a tasteless solution or an ice cream milkshake. They then looked at whether the volunteers who ate ice cream frequently showed less brain activity in the reward centres of the brain when drinking the ice cream milkshake.

The study excluded any individuals who were overweight or had reported binge eating in the past three months, as well as any who had used illegal drugs, took certain medications, had a head injury or a mental health diagnosis in the last year. The volunteers completed standard food questionnaires about their eating habits over the past two weeks, including how often they ate ice cream. They also answered questions about food cravings and how much they liked certain foods, including ice cream. The volunteers also had their weight, height and body fat measured.

Volunteers were asked to eat their meals as usual but not to eat anything for five hours before the brain scan. The researchers then gave them either a sip of chocolate ice cream milkshake or a tasteless solution, and monitored the activity in their brain. Each participant received both drinks in a randomised order. The researchers then looked at what happened in the brain during each drink, and whether this varied depending on how much ice cream the volunteer usually ate. They also looked at whether body fat or energy intake from other foods influenced the response.

 

What were the basic results?

The researchers found that when the volunteers drank the ice cream milkshake, it activated the parts of the brain involved in giving a pleasurable “reward” feeling. Volunteers who ate ice cream frequently showed less activity in these pleasurable reward areas in response to the milkshake. Percentage of body fat, total energy intake, percentage of energy from fat and sugar, and intake of other energy-dense foods were not related to the level of reward response to the milkshake.

 

How did the researchers interpret the results?

The researchers concluded that their findings show that frequent consumption of ice cream reduces the “reward” response in the brain to eating the food. They reported that a similar process is seen in drug addiction.

The researchers also said that understanding these sorts of processes could help us understand how changes in the brain may contribute to, and help maintain, obesity.

 

Conclusion

This brain-scanning study suggests that the brain’s pleasurable reward response to ice cream decreases if it is eaten frequently. There are some points to note:

  • The study only included healthy adolescents who were not overweight. Its results may not be representative of overweight or older individuals.
  • The study only tested one food, so the results may not apply to other foods.
  • Volunteers’ eating habits were only assessed for the past two weeks, and these may not be representative of their long-term eating habits.
  • The study did not look at any other food with a discernable taste, only a “tasteless liquid”. It would have been interesting to see whether the reward response with tasting other foods, including less energy dense foods, also diminished over time.
  • News reports of this research have claimed that this study shows that ice cream is “as addictive” as illegal drugs, but this is not the case. While the reduced brain reward seen with frequent ice cream eating was reportedly similar to that seen in the use of addictive drugs, the study unsurprisingly did not directly compare brain responses to ice cream and illegal drugs, or their addictive potential.

Analysis by Bazian

Links To The Headlines

Ice cream 'could be as addictive as cocaine', as researchers reveal cravings for the two are similar. Daily Mail, March 5 2012

Ice cream as 'addictive as drugs' says new study. The Daily Telegraph, March 5 2012

Links To Science

Burger KS and Stice E. Frequent ice cream consumption is associated with reduced striatal response to receipt of an ice cream–based milkshake. First published February 15 2012




05.03.2012 23:58:00

FROM THE ECONOMIST INTELLIGENCE UNIT


Greece's austerity measures are once again hitting the country's pharma industry, as cost-containment tightens.

The pain is far from over for pharma companies in Greece, as new cost-containment measures for the sector come into force. As part of its efforts to cut spending in the wake of its latest EU bailout, parliament has passed a new law limiting drug spending by the country's social insurance funds to ˆ2.88bn (US$3.8bn this year. The industry itself will be liable for any overspend.

The new law also makes it a criminal offence for doctors to prescribe drugs by brand rather than generic name. This draconian measure will apply to the top ten therapeutic classes from April 1st, and then to all drugs on the reimbursement list from June 1st. The country's reimbursement scheme will only cover the generic cost, with any additional cost to be covered by the patient. In addition, doctors will be fined if they fail to prescribe via the new electronic prescription system, while pharmacy opening hours will be extended.

The aim of these measures is to slice ˆ1bn off the country's drugs bill this year.
In December 2011, while Greece was negotiating its latest bailout, the EU and IMF reportedly asked for drug spending to be reduced to 1% of GDP. The Greek National Organisation for Medicines declared this goal was unrealistic. If the latest measures do succeed in cutting spend to ˆ2.88bn, then that will amount of around 1.4% of Greece's projected ˆ199bn in GDP this year.

The government also wants to raise the market share of generic drugs, which is currently one of the lowest in Europe at around 16% by volume in 2009, according to the
European Federation of Pharmaceutical Industries and Associations . Critics attribute this low share to the minimal difference between generic and branded drug prices, as well as incentives in the pharmacy sector which favoured more expensive drugs. The government has already moved to limit pharmacy profit margins to a flat fee, a measure that is expected to cut the number of pharmacies by 30% over the next few years.

These and other measures have already proved highly controversial. In May 2010, in the wake of previous austerity measures, pharma prices were cut by a weighted average of 21.5%, prompting protests from pharmaceutical producers. Two Danish pharmaceutical companies, Novo Nordisk and Leo Pharma, withdrew a number of their products from the Greek market (they reversed this action only after the government eased the price-cuts slightly .

Despite this, the government introduced a new referencing pricing system in September aligning Greek prices with the average of the three lowest-priced EU countries. The effect was to cut prices by a further 20%.  
As a result, Greece now has some of the lowest pharma prices in Europe, a fact that has prompted a huge parallel trade with other EU markets. Moreover, many hospitals have failed to pay for the drugs they have received, with debts to pharma companies deepening every month.

This latest announcement will lead to more controversy and further deter launches in the pharma sector. The government is clearly prepared for that, however. According to Pharma Times, ministers have in any case been contemplating banning new drug launches until such drugs have been accepted for reimbursement in 8-10 other EU countries. Though that measure would probably exclude cancer drugs, the main losers would be Greek patients.

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05.03.2012 21:19:20



Drug legalization in Central America merits a “serious” debate as a solution to the crime and violence coursing through the region even if it runs up against U.S. opposition, said Costa Rican President Laura Chinchilla.

“If we keep doing what we have been when the results today are worse than 10 years ago, we’ll never get anywhere and could wind up like Mexico or Colombia,” Chinchilla said yesterday in an interview in San Jose.

read more

http://www.cannabisculture.com/v2/content/2012/03/05/Costa-Rican-President-Calls-Drug-Legalization-Debate#comments



05.03.2012 15:00:00

by
Richard F. Kurz


DEA Badge.jpg
On February 29, a federal district court judge issued an
Order requiring that Cardinal Health, Inc. comply with an Immediate Suspension Order ("ISO" issued by the Drug Enforcement Administration ("DEA" . The court previously granted a temporary restraining order delaying Cardinal's compliance with the ISO, pending a decision on a preliminary injunction requested by Cardinal. However, the Court denied this preliminary injunction in its Order. Cardinal
appealed this decision on the same day as the court's Order.

Partially at issue in this dispute is the question of who is responsible for stopping diversion, a form of illegal sales of controlled drug substances. Diversion is distributing controlled drug substances to an entity without a valid DEA registration. In this case, diversion of the prescription pain killer oxycodone allegedly took place at pharmacies supplied by Cardinal's Lakeland, Florida distribution facility. Cardinal states that it has a system in place to stop diversion and that it is ready and willing to suspend shipments to any pharmacy that the DEA identifies as likely to be engaged in diversion. The DEA, however, states that the Lakeland facility has a continuing, affirmative obligation to police its retail customers to ensure that the controlled drug substances it provides are not being unlawfully diverted--and the Lakeland facility fell short of its legal and contractual obligations.

According to a
Complaint filed by Cardinal, the ISO requires the Lakeland facility to immediately halt shipments of all controlled drug substances to about 2,700 pharmacies, hospitals, and other customers to prevent alleged imminent danger to the public health or safety. Notably, only Cardinal's Lakeland facility is subject to the ISO. The DEA, however, does not allege that Cardinal itself distributed controlled drug substances to any entity not permitted to purchase them. Instead, the ISO was issued because four pharmacies that were supplied by the Lakeland facility have allegedly distributed oxycodone for illegitimate uses.

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05.03.2012 20:41:30

Lindsay Lohan's "Saturday Night Live" performance may not have been Emmy-worthy, but her efforts on the show could be the baby steps she needs to repair her long-tarnished brand.

"She showed that she wants to work again," Cooper Lawrence,
author of "Cult of Celebrity" told The Huffington Post. "She was relaxed, confident and professional. She may not have been funny the whole time, but she did show up, seemed sober and did not come off like a drug addict pulling the wool over our eyes. I was left with the feeling that she may be tired of being the punch line."

Lohan
received mixed reviews for her work on "SNL" this weekend, where she was quick to lampoon her past legal troubles and made light of the fact that she is often less than reliable, but she still wasn't able to pull off the kind of top-notch performance she proved she was capable of years ago when she hosted the show.

Still, following years of personal ups and downs and a handful of cancelled movie projects, simply not failing at the task put before her was enough for Lohan to start creeping her way back into the market as an actress, not a pin-up or a punchline.

"She was sober and knew that the critics would come down on her," said Hollywood publicist Michael Sands. "With her legal woes behind her ... perhaps she will take some acting classes and surprise us all."

"Do not count Lindsay out yet," he added.

However, not all critics were convinced that this weekend's show made the actress more viable as a real Hollywood player.

"Unless she's angling for a role as a not-terribly-adroit cue-card reader, or perhaps a sleepwalker, Lindsay Lohan didn't do her career any favors by hosting 'SNL,'" said April Bernard, the senior television editor for
Us Weekly
. "Referencing past successes such as a?˜Mean Girls,' as she did in one sketch, only reminded viewers how appealing she used to be. If she'd shown half the spark and talent that Maya Rudolph or Melissa McCarthy did this season, people would be talking about her comeback."

Love it or hate it, "SNL" was at least a minor step toward redemption for Lohan's brand --
a high-rated one at that-- but industry authorities believe it will take more than a few funny skits at her own expense to convince producers to take a chance on her as an actress again.

"Lohan's current brand rehabilitation tour -- including stops along the 'SNL' and 'Today' show highway -- have been orchestrated effectively but they hardly wipe away the memory of years of news coverage focused on her addictions, court appearances and her arrogance," said Mark Stevens,
author of "Your Marketing Sucks."

"There's always room for human redemption," he added, referencing former President Bill Clinton's rise from scandal. "But the directors and producers who hired her in the past still aren't going to be hiring Lindsay Lohan for the time being."

Head over here to see some of Lohan's "SNL" skits from the weekend.


http://www.huffingtonpost.com/2012/03/05/lindsay-lohan-snl_n_1321362.html#comments



cooksonb@sos.net (Cookson Beecher
05.03.2012 12:59:03
Despite a multitude of warnings about the dangers of drinking raw milk (milk that hasn't been pastuerized , why do some people continue to turn a deaf ear to those warnings, even in light of continued food poisoning outbreaks linked to raw milk?
Could it be the "messenger" -- typically federal and state agencies and public health officials?
A clue to that possibility surfaced in
a recent study, "Motivation for Unpasteurized Milk Consumption in Michigan, 2011," by Paul Bartlett and Angela Renee Katafiasz, of Michigan State University, which appeared in a recent issue of  "Food Protection Trends."
In an email to Food Safety News, Bartlett said that what surprised him the most about the results of the survey of raw-milk drinkers was that such a small percentage of them trusted public health officials regarding what food is safe to eat.
Only 4 (or 7.1 percent of the 56 raw-milk consumers who responded to the study's questionnaire agreed with a statement that "in general, they trusted recommendations made by state health officials about what foods are safe to eat." Another 10 (or 17.9 percent indicated they didn't agree with the statement, while another  41 (or 73.2 percent said they weren't sure.
"This lack of trust," says the study, "casts doubt on whether or not consumer education by local or state health departments would be effective in preventing milk-borne disease due to raw-milk consumption."
None of this surprises Mark McAfee, the outspoken co-owner of  California-based
Organic Pastures, the nation's largest raw-milk producer.  In an email to Food Safety News, McAfee said he has always thought that any area where raw milk is sold should have a huge ultra-red pink sign that says something like:  "The FDA says raw milk is dangerous because it has not been processed."
"If that were the case," he said, "sales would skyrocket. No one trusts the Food and Drug Administration or its propaganda." 
McAfee said the problem is that "state and federal agencies have cried wolf so many times against raw milk that now any cries that might be an honest attempt to warn of the rare incidence of illness is ignored as hatred against all things FDA."
FDA comes into the picture because the agency doesn't allow raw milk sold for human consumption to be transported across state lines.
That same skepticism about what public health officials and agencies have to say about raw milk kept surfacing in the recent Michigan study. When asked if raw milk should be regulated by the government to ensure quality standards, 27 (or 48.2 percent of the respondents disagreed, while only 9 (or 16.1 percent agreed.  Another 17 (or 30.4 percent said they weren't sure.
Along those same lines, some of the raw milk consumers in the study said they generally believe that their producers maintain a higher standard of animal care and cleanliness than does the mainstream dairy industry.
The respondents also took issue with some of the survey's other statements, once again revealing sharp differences of opinion with official government views on the potential health hazards of drinking raw milk.  For example, when asked if they agreed or disagreed with the statement that "Drinking raw milk increases your risk of getting a foodborne disease," an average of 44 (or 78.6 percent disagreed. Only 6 respondents agreed with the statement, and another 5 (or 8.9 percent of the respondents said they weren't sure.  In Februrary, the Centers for Disease Control and Prevention 
released a study showing that the rate of disease outbreaks linked to raw milk was 150 times greater than outbreaks linked to pasteurized milk.
 In 2010, Michigan had two
Campylobacter foodborne outbreaks associated with raw milk. And last year, 3 probable cases of
Q-fever were reported in people who participated in raw-milk cow-share arrangements, which according to the report, were presumably caused by drinking raw milk. Back in 1947, Michigan became the first state to require that all milk for sale be pasteurized. As such, the sale of raw milk for human consumption is illegal in that state. However cow- and goat-share agreements in which people buy a share of a herd and are therefore considered owners of the milk from the herd are permitted through an informal agreement on the part of the state.
Profile of a raw-milk drinker
The Michigan study starts off by acknowledging that "it is largely unknown why some consumers prefer raw milk over pasteurized milk."
As such, one of the goals of the peer-reviewed study was to come up with a some sort of profile of raw-milk drinkers in Michigan and from there, to summarize their reasons for preferring raw milk to pasteurized milk.
The profile that emerged was a well-educated adult in his/her late 20s who typically lives in a rural area. Overall, the ages of the raw-milk drinkers, which included family members, ranged from less than one year to 75.
The profile, which, co-author Bartlett readily says is limited due to the small number of raw-milk drinkers surveyed, contrasts starkly with a profile of raw-milk drinkers in California that emerged in an earlier report, "
Profile of Raw Milk Consumers."
Authored primarily by scientists then at FDA's Center for Food Safety and Applied Nutrition, the report analyzed responses to questions in the 1994 California Behavioral Risk Factor Surveillance System Survey that asked respondents about whether they drank raw milk, the amount consumed, the reason for drinking raw milk, and where raw milk was most often obtained.
 The researchers found that among the 3,999 survey respondents, 128 (about 3.2 percent reported drinking raw milk the previous year. These raw-milk consumers were more likely that those who didn't drink raw milk to be younger than 40, male, Hispanic and to have less than a high school education. 
However, these survey results included any responder who had drunk raw milk in the previous year no matter how much or how little.
One of the conclusions of the California report was that additional research is needed to further refine the profile of raw milk drinkers and determine their risk of adverse effects from drinking raw milk.
The report also said that "Although the role of raw milk as a vehicle in disease transmission has been well-documented, information regarding the prevalence of raw-milk consumption in sparse."
Estimates of the percentage of milk drinkers who drink raw milk range from 1 to 3 percent of the U.S. population, although no one knows for sure since it's too difficult to track the information.
Organic Pastures McAfee was happy to share some information about his raw-milk customers, based on informal studies and polls conducted by the dairy. What surfaces is that 50 percent of the dairy's raw-milk customers are well-educated moms between 20 and 45 years old. The rest of the dairy's raw-milk customers are what McAfee describes as "being all over the place" and can be anyone: young, old, fat, skinny, gay, straight, religious, agnostic, healthy, sick, abandoned by doctors, not wanting to go to doctors, Eastern Bloc immigrants, left wingers, right wingers, no wingers, Tea Party members, and homeschoolers.
"It is everyone," he said.
Why raw milk? 
Supporting local farms topped the list of the reasons the Michigan raw-milk survey respondents gave for preferring raw milk, with 48 (or 85.7 of them citing that as a reason. Next came taste, with 47 (or 83.9 percent giving that as a reason. "Holistic health benefits" were cited by 43 (or 76.8 percent of the respondents. Thirty-two respondents (or 57.1 percent said they don't feel processed milk is safe. A majority of the study's raw-milk drinkers shared their beliefs that raw milk was beneficial for relieving  digestive problems, intestinal diseases and allergies. Some said they believe raw milk is beneficial for heart disease, neurologic disease, acne, and cancer. Others shared anecdotal claims that when they drink pasteurized milk, they experience symptoms of lactose intolerance, which they said doesn't happen when they drink unpasteurized milk.  People with lactose intolerance have a hard time digesting lactose, which is a type of natural sugar found in milk and dairy products. The intolerance occurs when the small intestine doesn't make enough of the enzyme, lactase, which is needed to break down or digest lactose.  Symptoms include gas, belly pain, and bloating.
However, a 
study out of Stanford Medical School (financed by raw milk advocates not only raised questions about how widespread lactose intolerance really is, but found that raw milk did not confer any benefit over pasteurized milk in relieving symptoms of lactose intolerance. Health authorities say that no matter what benefits might be associated anecdotally with raw milk, the risk of contracting a foodborne disease such as E. coli, Salmonella, Campylobacter or Listeria infection outweighs any of the unproven benefits.  They point out that if harmful microorganisms from cow excrement contaminates the raw milk, those drinking it can come down with serious digestive problems, kidney failure, or even death.
In California, labels on raw-milk containers must say:  "Raw (unpasteurized milk and raw milk dairy products may contain disease-causing micro-organisms. Persons at highest risk of disease from these organisms include newborns and infants; the elderly; pregnant women; those taking corticosteroids, antibiotics or antacids; and those having chronic illnesses or other conditions that weaken their immunity."  The Michigan study also revealed that the average number of years the respondents have been drinking raw milk is 6.1 and that 92 percent of the milk the respondents' families drink is raw milk.
A commitment to purchasing raw milk can be seen in the average number of miles a respondent travels out of his or her way to buy raw milk: 24.2 miles. The average number of  pickups of raw milk each month was 4.1.
The study
Questionnaires were sent out to raw-milk producers, 20 of whom agreed to participate in the study. The producers, in turn, were sent survey questions, which they forwarded on to their cow- or goat-share members. Of the 160 questionnaires sent out, 56 were returned.
While the study has been criticized for being self-selecting in that it only questioned people who drink raw milk and biased because it started out with the assumption that it's potentially harmful to your health to drink raw milk, co-author Bartlett told Food Safety News that it was done "for the cost of postage" as a project for a 3-credit course. And, yes, he definitely would have liked to have had a higher response rate and a larger study.
He also pointed out that the hypothesized health benefits of raw milk are difficult to study because it would be unethical to randomly assign people to drink raw milk and others to drink pasteurized milk. Besides which, such a study could not be done blindly because the study subjects would certainly know if they were drinking raw or pasteurized milk (although the Stanford study effectively masked the taste differences with an added flavoring.
 More information about raw milk can be found
here



04.03.2012 21:28:49
Lindsay Lohan made a triumphant return to U.S. comedy show Saturday Night Live at the weekend as she poked fun at her legal woes, drug problems and lesbian past.



05.03.2012 21:43:52
Jennifer Aniston couldn't be happier to be out of New York for good. Plus, more celeb news in the Shortlist.

During the brief period when Jennifer Aniston shacked up with her boyfriend, Justin Theroux, in New York's West Village, the couple was reportedly hounded by paparazzi. At one point, it was even rumored that Justin's motorcycle had been covered in slices of Bologna. So we can hardly fault her for deciding to head back to the Left Coast, where celebs' privacy is protected by the gates on their mansions -- and off-street parking provides a safe harbor for their boyfriends' rides. "We tried New York," Jen tells People, but, "it felt like I was [living] in a fishbowl." A graduate of New York's LaGuardia High School of Music and Performing Arts, Jen adds that things have changed in the Big Apple since she last lived there. "Justin still has an apartment there," she says. "It was a little rough with the paparazzi. It didn't feel like the New York I grew up in and knew." Now that she's back in Los Angeles, however, the "Wanderlust" star says she's enjoying a "10-plus" happiness level and a Zen life. ( People

Just because Gwyneth Paltrow spends all her downtime searching for rare, overpriced species of Lacinato kale so GOOP readers have something tasty to tide them over between $400 GOOP cleanses, don't think she's unaware of how she comes off on her much-maligned blog. Gwynnie stopped by her chef-buddy Mario Batali's show, "The Chew," the other day, and managed to whip out a few zingers during the Celebrity Egg Timer segment. Asked when she had her last hangover, she nobly admitted, "after the Oscars." Asked what was the best thing her hubby, Chris Martin, ever cooked, she overshared, "Um, nothing." And finally, earning herself top marks in the self-deprecation category, she was asked what she'd call GOOP if it weren't called GOOP. Her reply? "SpoiledWhiteRichGirl.com." Touche, haters. ( Celebitchy RELATED: 2012 Oscar Afterparties

Attention, 11-year-old style mavens worldwide: Willow Smith wants you to express your individualism by sharing your dyed-green hair and tie-dye looks with like-minded 'tweens. Or, as she put it on her Instagram page alongside photos like this one of her verdant new hair-scape: "I am starting a LAGIT thingy with people around the world like @eeeeeeeeeeb ... Can share ALL of their styles... #uniqlook." The green 'do is Willow's third major hair change in as many weeks; in February, she shaved her head and later bleached what was left of her hair. ( JustJared RELATED: Very Bad Hair Day for Lindsay Lohan

We're not too surprised that Taylor Swift would want to cover up her black top with a colorful shawl in this tear sheet from the new Harper's Bazaar -- since the blouse underneath it is a design by her Grammy speech nemesis, Kanye West. Kissing and making up is just so much easier when a top fashion magazine is willing to pay you for it. ( Jezebel

When Pippa Middleton completed the Vasaloppet cross-country ski race in Sweden on Sunday, she was treated to a kiss -- from a total stranger. Almost as soon as Pippa crossed the finish line, student, part-time truck driver and event steward Erik Smedhs, rushed over to her and planted a wet one on the royal sister-in-law's flushed face. "For having been skiing for 56 miles she was surprisingly fresh," the audacious smoocher later told The Royalist. "I just thought it would be funny with all the commotion around her." His excuse for the bum-rush? "I told her that we have a tradition here in Mora when you reach the goal,and then I kissed her," he explained. "It actually is a tradition, but just for the winner of the race." Pippa came in at No. 421 in the women's section of the charity competition. ( DailyBeast

Kim Kardashian may have made $18 million off her 72-day marriage to Kris Humphries, but it looks like she won't be the only one to benefit from the short-lived union in the end. A letter was reportedly sent to each guest who attended Kim and Kris' wedding in which the bride explained that she would not be keeping any of the money she had been given as a gift. "I would like to thank you for your generous and thoughtful wedding gift," the letter reportedly said. "It has taken me some time to pull everything together but I wanted to let you know that the money for every gift received by me at my wedding has been donated to the Dream Foundation ..." A source confirms to Us that Kim donated twice the amount of money she received, putting hr check at about $200,000. According to its website, the charity focuses on "making dreams come true for adults facing life-threatening illness." ( TMZ RELATED: Did Kim Kardashian Diss Demi Moore Using a Devo Ditty?

As Brooke Mueller's legal team works on a plea deal related to her December drug and assault charges, the woman who was allegedly hit in the neck by Brooke at a club is complaining that Charlie Sheen's ex is getting off too easy. Despite being charged with felony possession of cocaine with intent to distribute and misdemeanor third degree assault, TMZ reports that Mueller will likely avoid jail time -- and Liana Little tells the site she's "furious." Little claims she bumped into Mueller in an Aspen, Colo., club, and the interaction led to a huge fight in which Mueller allegedly hit Little in the neck. Now Little wants to see Mueller go to jail. Mueller is expected to be sentenced at her next court date on April 2. ( TMZ

There's only one problem with Adele's new $11 million mansion that has two pools, 10 bedrooms and a tennis court: the ghosts. According to (an admittedly dubious new report from The Sun, the Grammy-winning singer is too freaked out by strange noises she hears in the night to sleep alone in her new digs. Instead, she's reportedly hired a female bodyguard as well as two new security staffers to help protect her from whatever creepiness may be lurking in the home, which was once a convent. ( NYPost RELATED: Adele: 'I'm Never Writing a Breakup Album Again'

Saturday, March 3, 2012

News and Events - 04 Mar 2012




02.03.2012 11:04:00

DOMINIC COYLE

Blockbuster drugs coming off patent will knock a major hole in our export figures and tax revenues

PHARMACEUTICALS HAVE been a driving force for Ireland’s export success in recent years. Even through the darkest days of our financial collapse and recession, the sector, dominated by the large multinational players, continued to deliver export growth and a glimmer of hope of economic recovery.

However, the most recent trade figures point to a looming problem for the Government. Reporting a 9 per cent fall in exports in December, the Central Statistics Office was unusually frank and detailed in stating that “a substantial part of the decline in the value of exports was due to a high value product in the chemicals and related products sector coming off patent”.

The drug is Lipitor, Pfizer’s blockbuster cholesterol lowering therapy and the world’s best-selling drug in recent years, accounting for revenues of $10.7 billion in 2010. Pfizer’s Cork plant produces 100 per cent of the company’s global requirements for the active pharmaceutical ingredient in the drug and a significant portion of the finished tablets.

Coming off patent will knock a major hole in the future revenues Pfizer can expect to get from the drug as generic competition kicks in. As a rule, loss of patent protection can hit the value of sales by anything between 40 and 70 per cent over time – and not much time at that.

For Ireland, the concern in the December figures was that, for now, generic competition to Lipitor is limited. If that was enough to skew the export figures so dramatically, the worry is what damage future, more intense competition will do to our trade balance.

And Lipitor is just one of a number of key drugs in which Ireland has a commercial interest and which are coming off patent. Chris van Egeraat, a lecturer in economic geography at NUI Maynooth, says seven of the 10 largest-selling drugs worldwide which are losing patent protection are currently produced in Ireland. They include the best-selling drug worldwide in 2010 after Lipitor; Sanofi/Bristol Myers Squibb’s blood clotting treatment Plavix, with sales of $9.43 billion. It comes off patent in May.

Globally, it is estimated that as much as $100 billion in sales will be lost to drug companies between 2009 and 2014 as a result of drugs coming off patent. Expected pipeline delivery in terms of market revenue over the same time amounts to about $30 billion, Dr van Egeraat says.

While he doesn’t expect the loss of patents to lead to huge imminent job losses, it does highlight the ambition of the Government’s new Action Plan for Jobs, which has targeted the health and life sciences sector for significant growth in the coming years to help reach the Government’s 100,000 job target.

However, loss of market sales will clearly impact on trade figures and tax revenues. The Irish Pharmaceutical Healthcare Association (IPHA notes that the pharmaceuticals sector accounts for roughly half of all exports and is the largest contributor to corporation tax, accounting for roughly 50 per cent of the ˆ3.5 billion collected last year.

In employment terms, IPHA president and Pfizer country manager David Gallagher says that about 25,000 people are employed directly in the industry, with a roughly similar number working in related sectors. He notes that pharmaceuticals has been more resilient than other sectors of the economy during recent “economically challenging times”.

The message is pointed, especially at a time when the sector is locked in a dispute with the Government over access to market for its new drugs and the contribution it can make to savings in the health budget sought by the State.

David Gallagher noted recently that an increasing number of innovative medicines are currently not being reimbursed by the Department of Health, despite being approved by regulators and meeting health technology assessments.

He recently accused the department of acting in bad faith by refusing to approve drugs for reimbursement as provided for under the industry’s current pricing agreement with the Department, even though the industry had delivered savings of about ˆ540 million over the past five years, a figure he says equates to a 20 per cent cut.

Even before the latest row, the IPHA said the delay between approval and market access had jumped by over 50 per cent to 157 days in recent years, and only 64 per cent of drugs that received market authorisation in the EU between 2007 and 2009 were made available to patients here.

Matt Moran, director of Ibec group PharmaChem Ireland, said Government policy “needs to urgently recognise the very serious challenges facing the industry”.

“A number of blockbuster drugs are coming off patent and healthcare spending in Ireland has been cut by ˆ600 million in the last five years,” he said. “The future success of the sector must not be taken for granted.”

In a speech last year, Gallagher said further price concessions were “simply untenable”, citing preliminary 2011 figures pointing to a 5.2 per cent decline in the value of the Irish market. “There is a limit to the amount which can be taken out of a market without its effective operation and employment being jeopardised,” he said.

Ireland is not alone. The commercial prospects for big pharma were also thrown into sharp focus with a report on the UK’s pharmaceuticals price regulation scheme, which reported collective industry losses of ?142 million in 2009 despite rising sales.

For its part, the Department of Health needs to find cuts in its budget. In a recent report on pharma pricing, the Economic and Social Research Institute (ESRI said that drug costs account for about 17.5 per cent of public health expenditure in Ireland, up from 14 per cent in 2000.

In 2009, the ESRI says, spending per head of population in Ireland on pharmaceuticals was “amongst the highest in the OECD”.

It is understood the Department of Health is targeting a saving of about ˆ112 million from the drugs bill – either in terms of pricing and access for new medicines or pricing of generics.

The ESRI report recommended a number of approaches. These included pricing drugs on the basis of the lowest cost in a basket of European markets rather than the average, and more regular price updates to capture the impact of falling prices earlier.

The industry says that, despite the small physical size of the Irish market, such a move would be negative in two ways. First, Ireland is itself a component of pricing baskets in eight other larger EU markets. A “match the lowest” price here will inevitably further eat into prices in other more important markets.

Secondly, the industry points to Ireland’s importance as a base of operations for most of the main players in the sector. An increasingly adversarial approach with the State will only damage the prospects for future investment, they say, with one industry source saying the recent approach of the department to market access for new drugs was creating a very poor impression in a number of important boardrooms State-side.

The seriousness with which the pharmaceutical sector views the current price negotiations in Ireland – where eight of the top 10 global players have operations – is highlighted by the engagement of some of the industry’s leading figures with the Government.

The chief executive of one major global player has made a point of briefly visiting Ireland next week. The message in his first visit to the State will not be lost on ministers. The following week, leading executives from another top 10 drug manufacturers gather in Dublin for a meeting at which the attitude of the State to the sector is certain to figure.

On the Government’s side, there is concern too at any adverse impact on such a major employer and contributor to the exchequer. Taoiseach Enda Kenny has recently engaged directly in private meetings with top industry figures here to assure them of the Government’s support despite the ongoing budgetary squeeze.

For their part, the drug companies say that current pricing pressures are restricting innovations. Without adequate compensation, they say, companies simply will not be able to invest in new products given the costs involved and the risk of failure.

This isn’t unique to Ireland. Reporting annual results earlier this month, Bayer chief executive Marijn Dekkers expressed concern “about the side-effects” of health service reforms taking place around the world “because the money we earn from today’s medicines pays for the development of tomorrow’s medicines”.

Pointing to the ˆ2 billion research and development cost of Xarelto, a new drug developed with Johnson Johnson to prevent blood clotting, he said: “We need innovative pharmaceuticals more than ever, because so many known diseases still cannot be treated adequately, or at all, with medicines.”

But that’s part of the problem for the major pharmaceutical companies. Many of the easy treatment areas are now well catered for. A good portion of the drugs that do so are shortly coming off patent and are easily accessible to generic competition.

The opportunities of the future lie in increasingly niche conditions or very high risk areas such as oncology and, especially, neurology. Added to this is the move to biologics and the trend towards more personalised medicines.

The challenge is evident in the fact that, last year, the US drug regulator, the Food and Drug Administration, licensed just a handful of new pharmaceutical therapies. Getting this more select group of drugs to as many markets as possible is increasingly critical for big pharma.

The age of the blockbuster is fading, along with the fat profit margins it offered. That presents major issues for the sector. Over time, through consolidation and acquisition, they have grown into massive unwieldy entities with poorly directed research failing to deliver sufficient pipeline.

In recent years, much effort has been devoted to streamlining operations and increasing productivity, especially on the research side. Thousands of jobs have been shed worldwide, and greater emphasis placed on outsourcing much of the early-stage RD work.

A case in point is Elan’s prospective Alzheimer’s treatment bapineuzumab. Originally developed by the company in association with Wyeth, it is now controlled by Pfizer (which acquired Wyeth to fill a perceived weakness in its biopharmaceuticals operations and Johnson Johnson, which bought an 18.4 per cent stake in Elan in 2009 in a deal valued at $1 billion. Its interest was driven largely by the Irish company’s pipeline – particularly bapineuzumab which is seen as one of the more promising candidates to address a disease with limited treatment options at present and which reports critical Phase III trial data later this year.

The second focus is on developing new markets. But that presents its own problems, not least with business practices that have reflected poorly on the industry.

Several of the largest drug companies have been implicated in an ongoing legal action in Serbia in which a group of 10 doctors and drug company officials were charged with taking, or offering, more than ˆ500,000 in bribes to use specific products. While all deny guilt in this case, an examination of US Securities and Exchange Commission (SEC filings by the world’s top 10 drug companies has found that eight of them recently warned of potential costs related to charges of corruption in overseas markets.

Life is unlikely to get any easier for the sector over the coming two or three years. That raises the stakes in the ongoing price negotiations. The new accord was due to come into force yesterday and, as the leaked Commission assessment this week illustrated, pressure on the Government to deliver the necessary savings to ensure their budgetary projections is only likely to intensify.

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03.03.2012 22:47:50
?Vice President Joe Biden is heading to Mexico and Honduras on Sunday in the midst of rapidly escalating demands by Latin American leaders that legalization should be included among the options for reducing drug-related violence, crime and mayhem.The presidents of Costa Rica, Guatemala, El Salvador, Colombia and Mexico, all struggling to stem the violence associated with a failing Drug War, have said in recent weeks they'd like to have a discussion on legalizing drugs, reports Martha Mendoza of The Associated Press.Meanwhile, Mexico, Argentina, Uruguay, and Peru already allow the possession of small amounts of marijuana for personal use, and the leaders of Brazil and Colombia are discussing alternatives to jailing drug users."U.S. government officials are worried because the smartest among them know that the current strategy, both domestically and internationally, cannot be defended on economic, scientific or ethical grounds," said Ethan Nadelmann, executive director of the Drug Policy Alliance (DPA .
Continue reading "VP Biden Visiting Latin America Amid Drug Legalization Debate" >



03.03.2012 16:37:00

Doctors can still get free samples of medicines, though not football tickets or lunch for their spouses, under a revised code of conduct drafted by a global drug industry trade group.

The new rules clarify the differences between gifts, promotional aids and items such as anatomical models that can be used in medical practice, the
International Federation of Pharmaceutical Manufacturers & Associations said today in a statement. The federation’s member companies will be required to adopt the new guidelines and provide related training to their 1.3 million employees, the group said.

The code may help curb legal expenses related to marketing, particularly in the U.S., where
GlaxoSmithKline Plc (GSK last year agreed to pay $3 billion to resolve criminal and civil investigations and other matters.
Pfizer Inc. (PFE and
Eli Lilly & Co. (LLY each paid more than $1 billion to settle marketing allegations in 2009.
Novartis AG (NOVN and
AstraZeneca Plc (AZN are among drugmakers that in the past year have disclosed U.S. subpoenas seeking information on the selling of certain products.

“The new code provides a framework for the industry to act with integrity and build trust,” AstraZeneca Chief Executive Officer David Brennan, the federation’s president, said in the statement. “This is not about doing the easy thing, but the right thing.”

Free Samples

Free samples of medicines may be given to doctors who are authorized to prescribe them to patients, the federation said in the code. Companies should avoid extravagant venues for meetings, be transparent in promotional materials, and shouldn’t offer items for the personal benefit of a doctor or nurse, such as gift certificates or concert tickets, according to the guidelines.

“As a general rule, the hospitality provided must not exceed what participants would normally be prepared to pay for themselves,” the federation said in the code. “Companies should not pay any costs associated with individuals accompanying invited health-care professionals.”

The rules don’t address direct-to-consumer advertising, pricing or other trade terms for supplying wholesalers and other commercial customers, or promotion of medical devices, the federation said. Drugmakers that fund patient advocacy groups shouldn’t insist on being the sole sponsor of such an organization, and should outline in writing the nature of the financial support, according to the code.

To contact the reporter on this story: Kristen Hallam in London at
khallam@bloomberg.net

To contact the editor responsible for this story: Phil Serafino at
pserafino@bloomberg.net

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01.03.2012 10:40:00

LONDON, March 1 | Thu Mar 1, 2012 6:00am GMT

LONDON, March 1

(Reuters - The global pharmaceutical industry is tightening its code of practice in a bid to stamp out bribery and corruption, particularly in emerging markets.

The International Federation of Pharmaceutical Manufacturers and Associations said on Thursday it had expanded and strengthened the code to ensure "the highest ethical and professional standards".

FREE GUIDES AND REPORTS FROM DIANOMI
ADVERTISEMENT

Bribes paid to foreign doctors and other state employees are shaping up as a major legal liability threat for Big Pharma, which has already forked out billions of dollars to settle mis-selling scandals in the United States.


Johnson & Johnson settled for $78 million with British and U.S. authorities last April, after disclosing payments to doctors in
Greece, Poland and Romania, while Pfizer reached an outline deal in a separate case late last year.


The new IFPMA code extends the rules covering drug company behaviour to also include interactions with medical institutions and patient organisations, as well as healthcare professionals, such as prescribing doctors.


It also makes clearer the dividing line between promotional aid and items of medical utility - which are allowed, and personal and cash gifts - which are not.


Permitted payments for entertainment are being curtailed, although they will still be allowed when interactions with drug firms are of a scientific or educational nature, including events at large medical meetings.


"The new code provides a framework for the industry to act with integrity and build trust," said IFPMA President and AstraZeneca CEO David Brennan. "This is not about doing the easy thing, but the right thing."


The Geneva-based organisation sees a particular role for its expanded code of practice in thinly regulated and smaller emerging markets, where national pharmaceutical organisations may have no presence.


But Tim Reed, director of Health Action International, an Amsterdam-based group that is critical of many industry practices, is not convinced the IFPMA has the teeth to make sure its edicts are implemented on the ground.


In the five years since the publication of the last code, the IFPMA has examined only four complaints against member companies - although more cases have been taken up by national organisations.


"There is a difference between intent and action," Reed said. "When you drill down to what is happening in developing countries, it is clear that it is just not applied. There is a real problem with enforcement because there is no punitive action as a result of transgression." (Editing by
Kate Kelland and
Jodie Ginsberg

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03.03.2012 23:05:37

Submitted by Brandon Smith from
Alt-Market

Americans Will Need “Black Markets” To Survive


As Americans, we live in two worlds; the world of mainstream fantasy, and the world of day-to-day reality right outside our front doors.  One disappears the moment we shut off our television.  The other, does not… 

When dealing with the economy, it is the foundation blocks that remain when the proverbial house of cards flutters away in the wind, and these basic roots are what we should be most concerned about.  While much of what we see in terms of economic news is awash in a sticky gray cloud of disinformation and uneducated opinion, there are still certain constants that we can always rely on to give us a sense of our general financial environment.  Two of these constants are supply and demand.  Central banks like the private Federal Reserve may have the ability to flood markets with fiat liquidity to skew indexes and stocks, and our government certainly has the ability to interpret employment numbers in such a way as to paint the rosiest picture possible, but ultimately, these entities cannot artificially manipulate the public into a state of demand when they are, for all intents and purposes, dead broke. 

In contrast, the establishment does have the ability to make specific demands or necessities illegal to possess, and can even attempt to restrict their supply.  Though, in most cases this leads not to the control they seek, but a sudden and sharp loss of regulation through the growth of covert trade.  The people need what the people need, and no government, no matter how titanic, can stop them from getting these commodities when demand is strong enough.

This process of removing necessary or desirable items from a trade environment leads inevitably to counter-prohibition often in the form of strict cash transactions, barter markets, or “black markets” as they are normally derided by those in power.  The problem for economic totalitarians is that the harder they squeeze the masses, the more intricate the rebellion becomes, especially when all they want is to participate in free markets the way our forefathers intended. 

The so called “drug war” is proof positive of the impossibility of locking down a product, especially one that has no moral bearing on the people who are involved in its use.  Only when a considerable majority of a populace can be convinced of the inherent immoral nature of an illicit item can its trade finally be squelched.  During any attempt to outlaw a form of commerce, a steady stream of informants convinced of their service to the “greater good” is required for success.  Dishonorable governments, therefore, do not usually engage in direct confrontation with black markets.  Instead, they seek to encourage the public to view trade outside mainstream legal standards as “taboo”.  They must condition us to react with guilt or misplaced righteousness in the face of black market activity, and associate its conduct as dangerous and destructive to the community, turning citizens into an appendage of the bureaucratic eye.

But, what happens when black markets, due to calamity, become a pillar of survival for a society?  What happens when the mainstream economy no longer meets the available demand?  What happens when this condition has been deliberately engineered by the power structure to hasten cultural desperation and dependence?

In this event, black markets not only sustain a nation through times of weakness, but they also become a form of revolution; a method for fighting back against the centralization of oppressive oligarchies and diminishing their ability to bottleneck important resources.  Black markets are a means of fighting back, and are as important as any weapon in the battle for liberty.  Here are just a few reasons why such organizational actions may be required in the near future…

The Mainstream Economy Is Slowly Killing Us

There are, unfortunately, some Americans out there who have not caught on yet to the grave circumstances in which we live.  Obviously, the stock market seems to have nearly recovered from its epic collapse in 2008 and 2009, and employment, according to the Labor Department, is on the mend.  The numbers say it all, right?  Wrong!  The numbers say very little, especially when they are a product of “creative mathematics”.

Despite the extreme spike in the Dow Jones since 2010, and all the talk of recovery, what the mainstream rarely mentions are the details surrounding this miraculous return from the dead for stocks. 

One of the most important factors to consider when gauging the health of the markets is “volume”; the amount of shares being traded and the amount of investors active on any given business day.  Since the very beginning of the Dow’s meteoric rise, the markets have been stricken with undeniably low volume interspersed with all too brief moments of activity.  In fact, this past January recorded the lowest NYSE volume since 1999:

http://www.bloomberg.com/news/2012-01-23/stock-trading-is-lowest-in-u-s-since-2008.html

Market volume has tumbled over 20% since last year, and is down over 50% from 2008 when the debt implosion began:


http://blogs.wsj.com/marketbeat/2012/02/24/trading-volume-anemic-this-year/

So then, if trade is sinking, why has the Dow jumped to nearly 13,000?  Low volume is the key.  In a low volume market, less individual investors are present to counteract the buying and selling of larger players, like international banks.  When this happens, the big boys are able to trigger market spikes, or market drops, literally at will.  Add to this the high probability that much of the stimulus that the Federal Reserve has regurgitated into the ether probably ended up in the coffers of corporate banks which then used the funny money to snap up equities, and presto!  Instant market rally!  But, a rally that is illusory and unstable.

Improving employment numbers are yet another financial hologram.  As most of us in the Liberty Movement are well aware, the Labor Department does not calculate true unemployment in the U.S.  Instead, it merely calculates those people who currently receive unemployment benefits.  Once a person hits the extension limit (99 weeks in many states on his benefits, he is removed from the rolls, and is no longer counted in the “official” unemployment percentage.  While Barack Obama and MSM pundits are quick to point out the drop in jobless to 8.3%, what they conveniently fail to mention is that MILLIONS of Americans have been unemployed for so long that they have been removed from the statistics entirely, and this condition is what has caused the primary fall in jobless percentages, not burgeoning business growth.

Roughly 11 million Americans who are jobless have nonetheless been excluded from the statistical government tally because of a loss of benefits:

http://dailycaller.com/2012/02/17/white-house-economic-report-hides-sharp-drop-in-number-of-working-americans/

According to the Congressional Budget Office, over 40% of the currently unemployed have been so for over 6 months.  It also points out that America is suffering the worst case of long term unemployment since the Great Depression:   


http://www.cbo.gov/sites/default/files/cbofiles/attachments/02-16-Unemployment.pdf

More than 10.5 million people in the U.S. also receive disability payments, which automatically removes them from the unemployment count, making it seem as though jobs are being created, rather than lost:


http://www.foxnews.com/politics/2012/02/19/report-millions-jobless-file-for-disability-when-unemployment-benefits-run-out/

Around 8.2 million Americans only work part time, meaning they work less hours than are generally considered to be necessary for self-support.  These people are still counted as “employed” even if they work a few hours a week.

True unemployment, according to John Williams of Shadowstats, is hovering near 23%:


http://www.shadowstats.com/alternate_data/unemployment-charts

Combine these circumstances with the ever weakening dollar, price inflation in foods and other commodities, and rocketing energy costs, and you have an economy that is strangling the life out of the middle-class and the poor in this country.  It is only a matter of time before the populace begins searching for alternative means of subsistence, even if that entails “illegal” activities.

Government Cracking Down On Freedom Of Trade

I was recently walking through the parking lot of a grocery store and ran into a group of women huddled intently around the back of a mini-van.  One of the women was reaching into a cooler and handing out glass containers filled with milk.  I approached to ask if she was selling raw milk, and if so, how much was she charging.  Of course, they turned startled and wide eyed as if I had just stumbled upon their secret opium ring.  Somehow it had slipped my mind how ferocious the FDA has become when tracking down raw milk producers.  The fact that these women were absolutely terrified of being caught with something as innocuous as MILK was disturbing to me.  How could we as a society allow this insanity on the part of our government to continue? 

That moment reminded me of the utter irrelevance of petty law, as well as the determination of human beings to defy such law. 

The Orwellian hammer has been thrust in the face of those who trade in raw milk, organic produce, and herbal supplements, while small businesses are annihilated by government dues and red tape.  In the meantime, law enforcement officials have been sent strapped to shut down children’s lemonade stands (no, seriously : 


http://www.cbsnews.com/2100-500164_162-20079838.html

Government legislation which would give the FDA jurisdiction over personal gardens has been fielded.  Retail gold and silver purchases of over $600 are now tracked and taxed.  The IRS even believes it has the right to tax barter exchanges, even though they do not explain how bartered goods could be legally qualified as “income”, or how they can conceive of ever being able to trace such private trade:

http://www.irs.gov/newsroom/article/0,,id=205581,00.html

Want to choose what kind of currency you would like to use to protect your buying power?  Not if  the Department Of Justice’s Anne Tompkins has anything to say about it. After the railroading of Liberty Dollar founder Bernard von NotHaus, she stated:


“Attempts to undermine the legitimate currency of this country are simply a unique form of domestic terrorism…”


“While these forms of anti-government activities do not involve violence, they are every bit as insidious and represent a clear and present danger to the economic stability of this country,” she added. “We are determined to meet these threats through infiltration, disruption, and dismantling of organizations which seek to challenge the legitimacy of our democratic form of government.”

http://www.fbi.gov/charlotte/press-releases/2011/defendant-convicted-of-minting-his-own-currency

As our economic situation grows increasingly precarious in this country, more and more people will turn towards localized non-corporate, non-mainstream business methods and products.  And, the government will no doubt attempt to greatly restrict or tax these alternatives.  This mentality is driven in part by their insatiable appetite for money, but mostly, it’s about domination.  They do what they do because they fear decentralized markets, and the ability of the citizenry to conceive of choices outside the system.  Slaves are not supposed to choose the economy they will participate in…

A “black market” is only a trade dynamic that the government disapproves of, and the government disapproves of most things these days.  Frankly, its time to stop worrying about what Washington D.C. consents to.  They have unfailingly demonstrated through rhetoric and action that they are not interested in the fiscal or social health of this nation, and so, we must take matters into our own hands. 

Black Market Advantages

If the events in EU nations such as Greece, Spain, and Italy are any indication, the U.S., with its massive debt to GDP ratio (real debt includes entitlement programs , is looking at one of two possible scenarios:  default, austerity measures, and high taxes, or, hyperinflation, and then default, austerity measures, and high taxes.  In the past we have mentioned barter networking and alternative market programs springing up in countries like Greece and Spain allowing the people to cope with the faltering economy.  Much of this trade is done away from the watchful eyes of government, simply because they cannot afford the gnashing buffalo-sized bites that bureaucrats would take from their savings in the process.  When a government goes rogue, and causes the people harm, the people are in no way obligated to continue supporting that government. 

Black markets give the citizenry a means to protest the taxation of a government that no longer represents them.  In a country stricken with austerity, these networks allow the public to thrive without having to pay for the mistakes or misdeeds of political officials and corporate swindlers.  In a hyperinflationary environment, black markets (or barter markets that have been deemed unlawful , can be used to supplant the imploding fiat currency altogether, and energize community markets that would otherwise be unable to function.  Ultimately, black markets feed and clothe the grassroots movement towards economic responsibility, and every man and woman with any sense of independence should rally around this resource with the intention to fight should it ever be threatened. 

“Legality” is arbitrary in the face of inherent conscience, or what some call “natural law”.  Without arbitrary legality, and unjust and unwarranted regulation, many federal alphabet agencies would not exist, including the FDA, the IRS, the EPA, the BLM, etc.  These institutions do not matter.  What they say has no meaning.  What matters is what is honorable, what is factual, and what is right.  Our loyalty, as Americans, is to our principles and our heritage.  Beyond that, we don’t owe anyone anything.  A black market in one place and time is a legitimate market in another.  For now, private localized trade is able to flow with only minor interference, but there will come a day when even the most practical and harmless personal transactions will be visited with administrative reproach and vitriol.  Alternative market champions will be accused of “extremism”, and undermining the mainstream economy.  We will be vilified as separatists, isolationists, terrorists, and traitors.  I believe it will be far more surreal than what we can possibly imagine now.  

They are welcome to call us whatever they like.  Honestly……who cares?  Let the paper pushers do their angry little dance.  The goal is freedom; in life, in politics, and in trade.    If we do not change how this country does business ourselves, the results will be far more frightening than any government agent at our doorstep, and the costs will be absolute…

http://www.zerohedge.com/news/guest-post-americans-will-need-%E2%80%9Cblack-markets%E2%80%9D-survive#comments



02.03.2012 15:00:00

by
Charles J. Raubicheck


Thumbnail image for Thumbnail image for FDA logo.jpg
FDA Commissioner Margaret Hamburg has announced Elizabeth ("Liz" Dickinson was appointed as the Chief Counsel of FDA, effective March 12, 2012.

The new Chief Counsel has had a long and distinguished career at FDA since she joined the agency in 1994. She has principally served as legal counsel to FDA's Center for Drug Evaluation and Research, providing advice in such key areas as Hatch-Waxman generic drug approvals, pediatric exclusivity and orphan drugs. She has also worked closely with the Department of Justice representing FDA in many court cases. Liz is well respected by both her colleagues at FDA and outside lawyers representing companies in FDA-regulated industries.

Among the imminent issues that Liz will face at FDA include generic drug user fees, drug shortages, and regulations/guidances for the Agency's implementation of new statutes on food safety and tobacco products.

Liz received her B.A. in Economics from the University of Massachusetts, and her J.D. from Northeastern University. She clerked for Judge William B. Bryant at the U.S. District Court for the District of Columbia.

Mark Raza will continue to serve as the Acting Principal Deputy Chief Counsel.

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02.03.2012 20:00:00
For the first time, an international collaborative prospective study led by Case Western Reserve University School of Medicine demonstrates the impact of ecstasy, a widely used illegal stimulant and hallucinogen with the scientific name of 3,4-methylenedioxymethamphetamine or MDMA, on fetal and infant development. The study, published in the February issue of Neurotoxicology and Teratology shows that in pregnant women using ecstasy, the chemical signaling that determines the baby's gender is affected and that the drug contributes to developmental delays in infants...